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DDR2 Antibody (TYRO10)

DDR2 Antibody (TYRO10) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDDR2 (TYRO10)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000
NotesTitration of the DDR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis DDR2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q16832
PurityPurified
Description MMP2 and MMP13, Promotes fibroblast migration and proliferation, Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2, Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, Required for normal bone development, [UniProt], and thereby contributes to cutaneous wound healing, and thereby facilitates cell migration and tumor cell invasion, cell migration and cell proliferation, remodeling of the extracellular matrix, DDR2/TYRO10 is a tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation
ImmunogenThis DDR2 antibody was produced from rabbits immunized with a his tag recombinant protein of human DDR2/TYRO10
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DDR2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDDR2 (TYRO10)
Short nameDDR2 Antibody (TYRO10)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namediscoidin domain receptor tyrosine kinase 2 (Antibody to) (TYRO10)
Alternative techniqueantibodies
Alternative to gene target BT, DDR2 and IDBG-104396 and ENSG00000162733 and 4921, Ddr2 and IDBG-203608 and ENSMUSG00000026674 and 18214, MIG20a and NTRKR3 and TKT and TYRO10, Plasma membranes, this GO :0001503 and ossification and biological process this GO :0003416 and endochondral bone growth and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0010715 and regulation of extracellular matrix disassembly and biological process this GO :0010763 and positive regulation of fibroblast migration and biological process this GO :0016324 and apical plasma membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005518: collagen binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005518: collagen binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0038062: protein tyrosine kinase collagen receptor activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0038062: protein tyrosine kinase collagen receptor activity, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030199 and collagen fibril organization and biological process this GO :0030500 and regulation of bone mineralization and biological process this GO :0031214 and biomineral tissue development and biological process this GO :0035988 and chondrocyte proliferation and biological process this GO :0038062 and protein tyrosine kinase collagen receptor activity and molecular function this GO :0038063 and collagen-activated tyrosine kinase receptor signaling pathway and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0090091 and positive regulation of extracellular matrix disassembly and biological process, 46641 and IDBG-629865 and ENSBTAG00000004885 and 533523, discoidin domain receptor tyrosine kinase 2
Identity 2731
Gene DDR2
Long gene name discoidin domain receptor tyrosine kinase 2
Synonyms gene TYRO10 NTRKR3
Synonyms gene name discoidin domain receptor family, member 2
Synonyms TKT
Locus 1q23, 3
Discovery year 1999-06-17
GenBank acession AK095975
Entrez gene record 4921
Pubmed identfication 9659899
RefSeq identity NM_006182
Classification Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000034423

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