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DEP1/PTPRJ Antibody

DEP1/PTPRJ Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDEP1/PTPRJ Primary Polyclonal Antibody
Also known asDEP1/PTPRJ PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDEP1/PTPRJ
SpecificityThis is a highly specific antibody against DEP1/PTPRJ
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range850-890/1337
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PTPRJ
Gene ID number5795
Swiss ProtQ12913
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen EGFR, Enhances the barrier function of epithelial junctions during reassembly, FLT3, Involved in vascular development, KDR, LYN, MAPK1, MAPK3, MET, Negative regulator of EGFR signaling pathway, Negative regulator of PDGF-stimulated cell migration, Negative regulator of cell proliferation, Negatively regulates T-cell receptor (TCR) signaling, OCLN, PDGFRB, PIK3R1 and PIK3R2, Plays a role in cell adhesion, Positive regulator of endothelial cell survival, Positive regulator of platelet activation and thrombosis, Positively affects cell-matrix adhesion, RET (variant MEN2A), Regulator of macrophage adhesion and spreading, SRC, TJP1, Upon T-cell TCR activation, as well as of VEGF-induced SRC and AKT activation, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling, it is up-regulated and excluded from the immunological synapses, migration, proliferation and differentiation, through EGFR dephosphorylation, through KDR dephosphorylation, through dephosphorylation of PDGFR, while upon T-cell-antigen presenting cells (APC) disengagement, Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CD148, DEP-1, Density-enhanced phosphatase 1, HPTP eta, HPTPeta, PTPRJ, Protein-tyrosine phosphatase eta, Protein-tyrosine phosphatase receptor type J, R-PTP-ETA, R-PTP-J, Receptor-type tyrosine-protein phosphatase eta, SCC1, DEP1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDEP1/PTPRJ
Short nameDEP1/PTPRJ Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDEP1/PTPRJ (Antibody to)
Alternative techniqueantibodies
Identity 9673
Gene PTPRJ
Long gene name protein tyrosine phosphatase, receptor type J
Synonyms DEP1 HPTPeta CD148
Locus 11p11, 2
Discovery year 1994-09-14
GenBank acession U10886
Entrez gene record 5795
Pubmed identfication 7937872 7994032
Classification Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type
Havana BLAST/BLAT OTTHUMG00000166573

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