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DERP6 Antibody, ALEXA FLUOR 488

DERP6 Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, DERP6 Polyclonal Antibody
Also known asAnti-DERP6 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDERP6
SpecificityThis is a highly specific antibody against DERP6
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DERP6/C17orf81
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen BRCA1 is directly involved in DNA repair, DERP6 is thought to be involved in p53-mediated transcriptional regulation, Expressed ubiquitously with highest expression in liver, Like p53, Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome, The gene encoding DERP6 maps to human chromosome 17, Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death, Two key tumor suppressor genes are associated with chromosome 17, brain and skeletal muscle, colon, heart, is a 316 amino acid protein that localizes to the cytoplasm and exists as multiple alternatively spliced isoforms, namely, p53 and BRCA1, prostate gland and fallopian tubes, testis, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, DERP6
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms DERP6
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DERP6 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetDERP6
Short nameDERP6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, DERP6 (Antibody to)
Alternative techniqueantibodies
Identity 30617
Gene ELP5
Long gene name elongator acetyltransferase complex subunit 5
Synonyms gene C17orf81
Synonyms gene name chromosome 17 open reading frame 81
Synonyms name dermal papilla derived protein 6 S-phase 2 protein
Locus 17p13, 1
Discovery year 2006-02-13
GenBank acession BC002762
Entrez gene record 23587
Pubmed identfication 22854966
RefSeq identity NM_015362
Classification Elongator acetyltransferase complex
Havana BLAST/BLAT OTTHUMG00000177974

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