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DERP6 Antibody, Biotin Conjugated

DERP6 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, DERP6 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDERP6
SpecificityThis is a highly specific antibody against DERP6
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DERP6/C17orf81
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BRCA1 is directly involved in DNA repair, DERP6 is thought to be involved in p53-mediated transcriptional regulation, Expressed ubiquitously with highest expression in liver, Like p53, Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome, The gene encoding DERP6 maps to human chromosome 17, Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death, Two key tumor suppressor genes are associated with chromosome 17, brain and skeletal muscle, colon, heart, is a 316 amino acid protein that localizes to the cytoplasm and exists as multiple alternatively spliced isoforms, namely, p53 and BRCA1, prostate gland and fallopian tubes, testis, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, DERP6
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms DERP6
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDERP6 Conjugated
Short name Conjugated, DERP6 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, DERP6 (Antibody to)
Alternative techniqueantibodies
Identity 30617
Gene ELP5
Long gene name elongator acetyltransferase complex subunit 5
Synonyms gene C17orf81
Synonyms gene name chromosome 17 open reading frame 81
Synonyms name dermal papilla derived protein 6 S-phase 2 protein
Locus 17p13, 1
Discovery year 2006-02-13
GenBank acession BC002762
Entrez gene record 23587
Pubmed identfication 22854966
RefSeq identity NM_015362
Classification Elongator acetyltransferase complex
Havana BLAST/BLAT OTTHUMG00000177974

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