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Desmin (Thr17) Antibody

Desmin (Thr17) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDesmin (Thr17) Primary Polyclonal Antibody
Also known asDesmin (Thr17) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDesmin Thr17
SpecificityThis is a highly specific antibody against Desmin Thr17
Modification(s)Phosphorylation
Modification site(s)Thr17
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human DES around the phosphorylation site of Thr17
Gene ID number1674
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A desmin related myopathy can have a distal onset, Antidesmin are useful in identification of tumours of myogenic origin, CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function, CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I), Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM), In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z line structures, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells, arrhythmias, it is then known as hereditary distal myopathy (HDM), restrictive heart failure, filaments found in muscle cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CMD1I, CSM1, CSM2, DES, DESM_HUMAN, Desmin phospho Thr17, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate filament protein, OTTHUMP00000064865, Desmin phospho Thr17
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene DSM1 and DSM2 play an important role in Desminopathy, Desmin regulated Myofibrilate Myopathy is a protein filament mutation of muscle proteins, Desmins or DES proteins detect by anti-desmin antibodies and DES ELISA kits
Gene targetDesmin (Thr17)
Short nameDesmin (Thr17) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDesmin (Thr17) (Antibody to)
Alternative techniqueantibodies

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