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DICER1 Antibody, Biotin Conjugated

DICER1 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, DICER1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDICER1
SpecificityThis is a highly specific antibody against DICER1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1330-1380/1922
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human DICER1
Gene ID number23405
Swiss ProtQ9UPY3
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, Gene silencing mediated by siRNAs, SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation, The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance, producing respectively short interfering RNAs (siRNA) and mature microRNAs, Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Dicer KIAA0928 K12H4, 8-LIKE HERNA
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDICER1 Conjugated
Short name Conjugated, DICER1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, DICER1 (Antibody to)
Alternative techniqueantibodies
Identity 17098
Gene DICER1
Long gene name dicer 1, ribonuclease III
Synonyms gene MNG1
Synonyms gene name Dcr-1 homolog (Drosophila) multinodular goitre 1 dicer 1, Dicer1, ribonuclease type III
Synonyms name dicer 1, double-stranded RNA-specific endoribonuclease
Locus 14q32, 13
Discovery year 2002-05-09
GenBank acession AB028449
Entrez gene record 23405
Pubmed identfication 10051563 10786632 21205968
Classification RNA helicases
Havana BLAST/BLAT OTTHUMG00000166134
Locus Specific Databases LRG_492

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