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Dio3 Antibody

Dio3 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameDio3 Primary Polyclonal Antibody
Also known asDio3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDio3
SpecificityThis is a highly specific antibody against Dio3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dio3
Gene ID number1735
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 3, Dio3 may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones and has been linked to the development of consumptive hypothyroidism in both infants and adults, It has an essential role for regulation of thyroid hormone inactivation during embryological development in that it catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3, respectively, 3', 3', 3'-diiodothyronine (T2), 5'-triiodothyronine (RT3) and 3, 5-triiodothyronine (T3) to inactive metabolites, Dio3 belongs to the iodothyronine deiodinase family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 5DIII, D3, DIOIII, Deiodinase iodothyronine type 3, Deiodinase iodothyronine type III, Dio 3, MGC124117, MGC124118, TXDI3, Type III 5' deiodinase, Type III iodothyronine deiodinase, Type 3 DI
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDio3
Short nameDio3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDio3 (Antibody to)
Alternative techniqueantibodies
Identity 12431
Gene TXDI3
Long gene name iodothyronine deiodinase 3
Synonyms gene name deiodinase, iodothyronine type III
Synonyms DIO3
Synonyms name thyroxine 5-deiodinase
Locus 14q32, 31
Discovery year 1996-04-09
GenBank acession S79854
Entrez gene record 1735
Pubmed identfication 9787088 7593630
RefSeq identity NM_001362
Classification Selenoproteins
Havana BLAST/BLAT OTTHUMG00000160681

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