Name : Dio3 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6177971288
| Long name | Dio3 Primary Polyclonal Antibody |
| Also known as | Dio3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Dio3 |
| Specificity | This is a highly specific antibody against Dio3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dio3 |
| Gene ID number | 1735 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | 3, Dio3 may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones and has been linked to the development of consumptive hypothyroidism in both infants and adults, It has an essential role for regulation of thyroid hormone inactivation during embryological development in that it catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3, respectively, 3', 3', 3'-diiodothyronine (T2), 5'-triiodothyronine (RT3) and 3, 5-triiodothyronine (T3) to inactive metabolites, Dio3 belongs to the iodothyronine deiodinase family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 5DIII, D3, DIOIII, Deiodinase iodothyronine type 3, Deiodinase iodothyronine type III, Dio 3, MGC124117, MGC124118, TXDI3, Type III 5' deiodinase, Type III iodothyronine deiodinase, Type 3 DI |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Dio3 |
| Short name | Dio3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Dio3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 12431 |
| Gene | TXDI3 |
| Long gene name | iodothyronine deiodinase 3 |
| Synonyms gene name | deiodinase, iodothyronine type III |
| Synonyms | DIO3 |
| Synonyms name | thyroxine 5-deiodinase |
| Locus | 14q32, 31 |
| Discovery year | 1996-04-09 |
| GenBank acession | S79854 |
| Entrez gene record | 1735 |
| Pubmed identfication | 9787088 7593630 |
| RefSeq identity | NM_001362 |
| Classification | Selenoproteins |
| Havana BLAST/BLAT | OTTHUMG00000160681 |