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DLK Antibody

DLK Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDLK
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the DLK antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis DLK antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P80370
PurityAntigen affinity
Description A polymorphism within this gene has been associated with child and adolescent obesity, Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14), It is one of several imprinted genes located in a region of on chr 14q32, The mode of inheritance for this polymorphism is polar overdominance, The protein is involved in the differentiation of several cell types, This gene is expressed from the paternal allele, including adipocytes, it is also thought to be a tumor suppressor, this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass, This gene encodes a transmembrane protein containing six epidermal growth factor repeats
ImmunogenThis DLK antibody was produced from rabbits immunized with a recombinant protein of human DLK
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DLK antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDLK
Short nameDLK Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDLK (Antibody to)
Alternative techniqueantibodies
Identity 6851
Gene MAP3K12
Long gene name mitogen-activated protein kinase kinase kinase 12
Synonyms gene ZPK
Synonyms MUK DLK ZPKP1 MEKK12
Synonyms name dual leucine zipper kinase DLK
Locus 12q13, 13
Discovery year 1994-09-29
GenBank acession U07358
Entrez gene record 7786
Pubmed identfication 8037767
RefSeq identity NM_006301
Classification Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT OTTHUMG00000169854

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