Name : DLP1 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5249700083
| Long name | Biotin Conjugated, DLP1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DLP1 |
| Specificity | This is a highly specific antibody against DLP1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 50-100/736 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human DNM1L |
| Gene ID number | 10059 |
| Swiss Prot | O00429 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Also required for mitochondrial fission during mitosis, Facilitates developmentally regulated apoptosis during neural tube formation, Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed, Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism, Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles, Required for a normal rate of cytochrome c release and caspase activation during apoptosis, Required for formation of endocytic vesicles, Required for normal brain development, Required for programmed necrosis execution, Through its function in mitochondrial division, by suppressing oxidative damage, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, including that of cerebellum, the function may require its recruitment by MFF to clathrin-containing vesicles, this requirement may depend upon the cell type and the physiological apoptotic cues, Functions in mitochondrial and peroxisomal division |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | DLP1, DNM1L, DRP1, DVLP, Dnm1p/Vps1p-like protein, Dymple, Dynamin family member proline-rich carboxyl-terminal domain less, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, Dynamin-related protein 1, HdynIV, Dynamin-1-like protein |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DLP1 Conjugated |
| Short name | Conjugated, DLP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, DLP1 (Antibody to) |
| Alternative technique | antibodies |