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DMP1 Antibody, ALEXA FLUOR 488

DMP1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, DMP1 Polyclonal Antibody
Also known asAnti-DMP1 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDMP1
SpecificityThis is a highly specific antibody against DMP1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DMP1
Gene ID Number1758
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen DMP-1 is expressed in bone, DMP-1 is proteolytically processed into N- and C-terminal fragments in the ECM of bone and dentin, DMP-1 is then exported to the extracellular matrix (ECM) where it regulates the nucleation of hydroxyapatite and the formation of calcified tissue, DMP-1 localizes to the nucleus of undifferentiated osteoblasts where it functions as a transcriptional regulator for osteoblast-specific gene activation and induces osteoblast differentiation, DMP-1 undergoes a conformational change and becomes phosphorylated by casein kinase II in response to an influx of calcium ions to the nucleus, During osteoblast maturation, It is important for the mineralization of bone and dentin, It is synthesized by preosteoblasts and contains a large number of acidic domains, The protein has also been identified in bone as a high molecular weight proteoglycan comprised of the N-terminal DMP-1 fragment and chondroitin sulfate, tooth and hypertrophic cartilage, DMP-1 is a member of the small integrin ligand N-linked glycoprotein family, The loss of DMP-1 can result in hypomineralized bone
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DMP1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetDMP1
Short nameDMP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, dentin matrix acidic phosphoprotein 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ARHP and ARHR and DMP-1, DMP1 and IDBG-29190 and ENSG00000152592 and 1758, DMP1 and IDBG-643326 and ENSBTAG00000019132 and 281118, Dmp1 and IDBG-185392 and ENSMUSG00000029307 and 13406, extracellular matrix binding, nuclei, this GO :0001503 and ossification and biological process this GO :0005178 and integrin binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0010811 and positive regulation of cell-substrate adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0031214 and biomineral tissue development and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0050840 and extracellular matrix binding and molecular function, this GO :0005178: integrin binding, this GO :0005178: integrin binding and also this GO :0005509: calcium ion binding and also this GO :0050840: extracellular matrix binding, this GO :0005509: calcium ion binding, this GO :0050840: extracellular matrix binding, dentin matrix acidic phosphoprotein 1
Identity 2932
Gene DMP1
Long gene name dentin matrix acidic phosphoprotein 1
Synonyms gene name dentin matrix acidic phosphoprotein
Locus 4q22, 1
Discovery year 1995-08-10
GenBank acession U34037
Entrez gene record 1758
Pubmed identfication 8586437 9177774
Classification SIBLING family
Havana BLAST/BLAT OTTHUMG00000130598

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