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DNA PKcs ANTIBODY, Cy3 Conjugated

DNA PKcs ANTIBODY, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, DNA PKcs POLYCLONAL ANTIBODY
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDNA PKcs
SpecificityThis is a highly specific antibody against DNA PKcs
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DNA PKcs
Gene ID number5591
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Ability to phosphorylate TP53/p53 in the presence of supercoiled DNA is dependent on C1D, Also involved in modulation of transcription, Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA, DHX9, Found at the ends of chromosomes, HSPCA, Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination, May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage, Must be bound to DNA to express its catalytic properties, PARP1, POU2F1, Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, Phosphorylates DCLRE1C, Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C), Recognizes the substrate consensus sequence [ST]-Q, Required to protect and align broken ends of DNA, SRF, The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step, WRN, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, c-Abl/ABL1, c-jun/JUN, c-myc/MYC and RFA2, histone H1, p53/TP53, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion, thereby regulating DNA damage response mechanism, Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms DNA-PK catalytic subunit, DNA-PKcs, DNAPK, DNAPK catalytic subunit, DNPK1, HYRC, HYRC1, PRKDC, PRKDC, PRKDC_HUMAN, Protein Kinase DNA Activated Catalytic Polypeptide, Variant, XRCC 7, XRCC7, p350, p460, DNA-dependent protein kinase catalytic subunit
Properties 1 of the DNA PKcs ANTIBODY, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser
Gene targetDNA PKcs Conjugated
Short name Conjugated, DNA PKcs ANTIBODY
Techniqueantibody Conjugates
LabelCy3
Alternative name cyanine 3 coupled, Desoxyribonucleic acid PKcs (Antibody to)

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