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Dnmt3b Antibody

Dnmt3b Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDnmt3b
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:10-1:50, Western blot: 1:2000
NotesTitration of the Dnmt3b antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis Dnmt3b antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9UBC3
PurityPurified
Description Dnmt3b is a DNA methyltransferase which is thought to function in de novo methylation, Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF)syndrome, Studies in mice have demonstrated that DNA methylation is required for mammalian development, The protein localizes primarily to the nucleus and its expression is developmentally regulated, and X-chromosome inactivation, imprinting, rather than maintenance methylation, CpG methylation is an epigenetic modification that is important for embryonic development
ImmunogenA portion of amino acids 389-417 from the human protein was used as the immunogen for this Dnmt3b antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Dnmt3b antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDnmt3b
Short nameDnmt3b Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDnmt3b (Antibody to)
Alternative techniqueantibodies
Identity 2979
Gene DNMT3B
Long gene name DNA methyltransferase 3 beta
Synonyms gene name DNA (cytosine-5-)-methyltransferase 3 beta
Locus 20q11, 21
Discovery year 1998-07-15
Entrez gene record 1789
Pubmed identfication 9662389 10433969
RefSeq identity NM_006892
Classification PWWP domain containing
Havana BLAST/BLAT OTTHUMG00000032226
Locus Specific Databases DNMT3Bbase: Mutation registry for ICF syndrome LRG_56

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