Name : DOCK8 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN5412675908
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | DOCK8 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | Western blot: 1:1000-2000 |
| Intented use | This DOCK8 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID # | 81704 |
| Uniprot # | Q8NF50 |
| Purity | Antigen affinity |
| Description | GEF proteins activate some small GTPases by exchanging bound GDP for free GTP (By similarity), Dedicator of cytokinesis protein 8 is a potential guanine nucleotide exchange factor (GEF) |
| Immunogen | A portion of amino acids 2056-2090 from the human protein was used as the immunogen for the DOCK8 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DOCK8 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | DOCK8 |
| Short name | DOCK8 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | dedicator on cytokinesis 8 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DOCK8 and IDBG-43444 and ENSG00000107099 and 81704, DOCK8 and IDBG-631748 and ENSBTAG00000002190 and 100295817, Dock8 and IDBG-154888 and ENSMUSG00000052085 and 76088, Plasma membranes, protein binding, this GO :0001771 and immunological synapse formation and biological process this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0016020 and membrane and cellular component this GO :0031252 and cell leading edge and cellular component this GO :0036336 and dendritic cell migration and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0061485 and memory T cell proliferation and biological process this GO :0070233 and negative regulation of T cell apoptotic process and biological process, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005488: binding and also this GO :0005515: protein binding, this GO :0005488: binding, this GO :0005515: protein binding, dedicator of cytokinesis 8 |
| Identity | 19191 |
| Gene | DOCK8 |
| Long gene name | dedicator of cytokinesis 8 |
| Synonyms | FLJ00026 FLJ00152 ZIR8 FLJ00346 |
| Locus | 9p24, 3 |
| Discovery year | 2003-12-02 |
| GenBank acession | AK090429 |
| Entrez gene record | 81704 |
| Pubmed identfication | 11214971 |
| RefSeq identity | XM_036307 |
| Havana BLAST/BLAT | OTTHUMG00000078789 |
| Locus Specific Databases | LRG_196 |