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DOG-1/ ANO1 Antibody

DOG-1/ ANO1 Antibody size: 100ug 354

Supplier MBS MONO
Price 354
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asDOG-1
Other names Anoctamin-1, Ca2+-activated Cl- channel, Discovered on gastrointestinal stromal tumors protein 1, Oral cancer overexpressed protein 2, Transmembrane protein 16A, Tumor-amplified and overexpressed sequence 2, anoctamin 1, anoctamin-1, calcium activated chloride channel, discovered on gastrointestinal stromal tumors protein 1, oral cancer overexpressed 2, transmembrane protein 16A (eight membrane-spanning domains), tumor-amplified and overexpressed sequence 2, anoctamin-1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameTMEM16A
Gene name synonimsN/A
Other gene names ANO1, DOG1, DOG1, ORAOV2, ORAOV2, TAOS2, TAOS2, TMEM16A, TMEM16A, ANO1
ClonalityMonoclonal
Immunoglobulin isotype kappa, IgG1
CloneDG1/447
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity 94, DOG-1 is rarely expressed in other soft tissue tumors, Immunoreactivity for DOG-1 has been reported in 97, Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The overall sensitivity of DOG1 and c-kit in GIST's is nearly identical: 94, This particular antibody might cross react with speacies outside of the listed ones, c-kit signaling-driven mesenchymal tumors of the GI tract, due to appearance, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen, including all c-kit negative GIST's, may be difficult to diagnose, which, 4% vs, 7%, 8 percent of scorable GIST's, Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST's)
Purification methodN/A
Form/AppearanceN/A
ConcentrationN/A
Storage and shipping Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene target1/ ANO1
Short nameDOG-1/ ANO1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namecanine-1/ ANO1 (Antibody to)
Alternative techniqueantibodies
Identity 21625
Gene ANO1
Long gene name anoctamin 1
Synonyms gene ORAOV2 TMEM16A
Synonyms gene name calcium activated chloride channel , oral cancer overexpressed 2 transmembrane protein 16A anoctamin 1
Synonyms TAOS2 FLJ10261 DOG1
Locus 11q13, 3
Discovery year 2003-10-16
GenBank acession BC033036
Entrez gene record 55107
Pubmed identfication 15067359 18724360 24692353
RefSeq identity NM_018043
Classification Anoctamins
Havana BLAST/BLAT OTTHUMG00000167204

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