Name : DOK1(Tyr362) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN4319901427
| Long name | DOK1(Tyr362) Primary Polyclonal Antibody |
| Also known as | DOK1(Tyr362) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | DOK1 Tyr362 |
| Specificity | This is a highly specific antibody against DOK1 Tyr362 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Tyr362 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr362 |
| Gene ID number | 1796 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs, Docking protein 2 binds p120 (RasGAP) from CML cells, It has been postulated to play a role in mitogenic signaling, It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML, Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DOK 1, DOK-1, DOK1, DOK1 phospho Tyr362, DOK1_HUMAN, Docking protein 1, Docking protein 1 62kD, Docking protein 1 62kD, Docking protein 1 p62dok Downstream of tyrosine kinase 1 pp62, Downstream of tyrosine kinase 1, P62DOK, docking protein 1 62kD downstream of tyrosine kinase 1, docking protein 1 downstream of tyrosine kinase 1, p-DOK1 phospho Y362, p62dok, pp62, pp62, DOK1 phospho Y362 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DOK1(Tyr362) |
| Short name | DOK1(Tyr362) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 62kDa (downstream on tyrosine kinase 1)(Tyr362) (Antibody to), docking protein 1 |
| Alternative technique | antibodies |
| Alternative to gene target | 62kDa (downstream of tyrosine kinase 1), DOK1 and IDBG-57879 and ENSG00000115325 and 1796, DOK1 and IDBG-631228 and ENSBTAG00000018579 and 514962, Dok1 and IDBG-159342 and ENSMUSG00000068335 and 13448, P62DOK, nuclei, protein binding, this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005158 and insulin receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component, this GO :0005057: receptor signaling protein activity, this GO :0005057: receptor signaling protein activity and also this GO :0005158: insulin receptor binding and also this GO :0005515: protein binding, this GO :0005158: insulin receptor binding, this GO :0005515: protein binding, docking protein 1 |
| Identity | 2990 |
| Gene | DOK1 |
| Long gene name | docking protein 1 |
| Synonyms gene name | 62kD (downstream of tyrosine kinase 1) docking protein 1, 62kDa (downstream of tyrosine kinase 1) , docking protein 1 |
| Synonyms | p62dok |
| Synonyms name | downstream of tyrosine kinase 1 |
| Locus | 2p13, 1 |
| Discovery year | 1997-07-25 |
| GenBank acession | U70987 |
| Entrez gene record | 1796 |
| Pubmed identfication | 9008160 9790776 15546884 |
| RefSeq identity | NM_001381 |
| Havana BLAST/BLAT | OTTHUMG00000129956 |