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DTX3L Antibody

DTX3L Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDTX3L Primary Polyclonal Antibody
Also known asDTX3L PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDTX3L
SpecificityThis is a highly specific antibody against DTX3L
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range720-738/740
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DTX3L
Gene ID number151636
Swiss ProtQ8TDB6
Tested ApplicationsWB
Recommended dilutionsWB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen In concert with PARP9, Involved in the recruitment of 53BP1/TP53BP1 to sites of DNA damage by mediating H4K91ub1 formation, PARP1-dependent PARP9-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, Protects cells exposed to DNA-damaging agents, The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 'Lys-20' methylation (H4K20me), UIMC1/RAP80, and BRCA1 to DNA damage sites, in response to DNA damage, plays a role in PARP1-dependent DNA damage repair, Ubiquitin ligase that mediates monoubiquitination of 'Lys-91' of histone H4 (H4K91ub1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names B-lymphoma- and BAL-associated protein, DTX3L, E3 ubiquitin-protein ligase DTX3L, Protein deltex-3-like, Rhysin-2, Rhysin2, BBAP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDTX3L
Short nameDTX3L Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDTX3L (Antibody to)
Alternative techniqueantibodies
Identity 30323
Gene DTX3L
Long gene name deltex E3 ubiquitin ligase 3L
Synonyms gene name deltex 3-like (Drosophila)
Synonyms BBAP
Synonyms name rhysin 2
Locus 3q21, 1
Discovery year 2004-12-03
Entrez gene record 151636
Pubmed identfication 12670957 22411408
RefSeq identity NM_138287
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000159524

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