Name : DUX4 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1116288899
| Long name | DUX4 Primary Polyclonal Antibody |
| Also known as | DUX4 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | DUX4 |
| Specificity | This is a highly specific antibody against DUX4 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DUX4 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Approximately 70-90% of individuals have inherited the disease-causing deletion from a parent, Defects in DUX4 may be the cause of facioscapulohumeral muscular dystrophy (FSHD), FSHD is characterized by weakness of the muscles of the face, Offsprings of an affected individual have a 50% chance of inheriting the deletion, Severity is highly variable, Weakness is slowly progressive and about 20% of affected individuals eventually require a wheelchair, and approximately 10-30% of affected individuals have FSHD as the result of a de novo deletion, upper-arm and shoulder girdle, DUX4 is a homeodomain protein with a similar protein sequence to Pax3 and Pax7 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DUX10, DUX4_HUMAN, Double homeobox protein 4, Double homeobox protein 4/10, Double homeobox protein 10 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DUX4 |
| Short name | DUX4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | DUX4 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 50800 |
| Gene | DUX4 |
| Long gene name | double homeobox 4 |
| Locus | 4q35, 2 |
| Discovery year | 2014-06-20 |
| Entrez gene record | 100288687 |
| Pubmed identfication | 20724583 |
| Havana BLAST/BLAT | OTTHUMG00000175568 |