| Long name | E2F1 (Ser364) Primary Polyclonal Antibody |
| Also known as | E2F1 (Ser364) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | E2F1 Ser364 |
| Specificity | This is a highly specific antibody against E2F1 Ser364 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser364 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 350-370/437 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic phosphopeptide derived from human E2F1 around the phosphorylation site of Ser364 |
| Gene ID number | 1869 |
| Swiss Prot | Q01094 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication, E2F1 binds preferentially RB1 in a cell-cycle dependent manner, It can mediate both cell proliferation and TP53/p53-dependent apoptosis, The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase, Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | E2F-1, E2F1, PBR3, RBAP-1, RBAP1, RBBP-3, RBBP3, Retinoblastoma-associated protein 1, Retinoblastoma-binding protein 3, Transcription factor E2F1, pRB-binding protein E2F-1, RBP3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | E2F1 (Ser364) |
| Short name | E2F1 (Ser364) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | E2F transcription factor 1 (Ser364) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0030900 and forebrain development and biological process this GO :0035189 and Rb-E2F complex and cellular component this GO :0043276 and anoikis and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048255 and mRNA stabilization and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0071398 and cellular response to fatty acid and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071930 and negative regulation of transcription involved in G1/S transition of mitotic cell cycle and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1900740 and positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and biological process this GO :1990086 and lens fiber cell apoptotic process and biological process this GO :2000045 and regulation of G1/S transition of mitotic cell cycle and biological process, E2F-1 and RBAP1 and RBBP3 and RBP3, E2F1 and IDBG-67214 and ENSG00000101412 and 1869, E2f1 and IDBG-210416 and ENSMUSG00000027490 and 13555, nuclei, sequence-specific DNA binding, this GO :0000077 and DNA damage checkpoint and biological process this GO :0000080 and mitotic G1 phase and biological process this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000085 and mitotic G2 phase and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0001047 and core promoter binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0001047: core promoter binding, this GO :0001047: core promoter binding and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003714: transcription corepressor activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0043565: sequence-specific DNA binding, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003714: transcription corepressor activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0043565: sequence-specific DNA binding, 78028 and IDBG-641855 and ENSBTAG00000003971 and 535369, E2F transcription factor 1 |
| Identity | 3113 |
| Gene | E2F1 |
| Long gene name | E2F transcription factor 1 |
| Synonyms gene | RBBP3 |
| Synonyms | RBP3 |
| Locus | 20q11, 22 |
| Discovery year | 1993-06-29 |
| Entrez gene record | 1869 |
| Pubmed identfication | 8964493 |
| Classification | E2F transcription factors |
| Havana BLAST/BLAT | OTTHUMG00000032265 |
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