| Long name | ECT2 (Thr373) Primary Polyclonal Antibody |
| Also known as | ECT2 (Thr373) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ECT2 Thr373 |
| Specificity | This is a highly specific antibody against ECT2 Thr373 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Thr373 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human ECT2 around the phosphorylation site of Thr373 |
| Gene ID number | 1894 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver, The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases, Thus, [provided by RefSeq], and is thought to have an important role in the regulation of cytokinesis, this protein is expressed in a cell cycle-dependent manner during liver regeneration, The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ECT 2, ECT-2, ECT2, ECT2 phospho Thr373, ECT2 protein, ECT2_HUMAN, Epithelial cell transforming sequence 2, Epithelial cell transforming sequence 2 oncogene, Epithelial cell transforming sequence 2 oncogene protein, Epithelial cell-transforming sequence 2 oncogene, FLJ10461, MGC138291, Protein ECT2, p-ECT2 Thr373, ECT2 phospho T373 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ECT2 (Thr373) |
| Short name | ECT2 (Thr373) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | epithelial cell transforming sequence 2 oncogene (Thr373) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | ARHGEF31, BT, ECT2 and IDBG-65239 and ENSG00000114346 and 1894, Ect2 and IDBG-134125 and ENSMUSG00000027699 and 13605, nuclei, protein homodimerization activity, this GO :0000902 and cell morphogenesis and biological process this GO :0000910 and cytokinesis and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0015031 and protein transport and biological process this GO :0017048 and Rho GTPase binding and molecular function this GO :0030496 and midbody and cellular component this GO :0032147 and activation of protein kinase activity and biological process this GO :0032154 and cleavage furrow and cellular component this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0032467 and positive regulation of cytokinesis and biological process this GO :0032862 and activation of Rho GTPase activity and biological process this GO :0032863 and activation of Rac GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0042307 and positive regulation of protein import into nucleus and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043089 and positive regulation of Cdc42 GTPase activity and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045859 and regulation of protein kinase activity and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051988 and regulation of attachment of spindle microtubules to kinetochore and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0070830 and tight junction assembly and biological process this GO :0071277 and cellular response to calcium ion and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0072686 and mitotic spindle and cellular component this GO :0097149 and centralspindlin complex and cellular component this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005089: Rho guanyl-nucleotide exchange factor activity and also this GO :0005096: GTPase activator activity and also this GO :0005515: protein binding and also this GO :0017048: Rho GTPase binding and also this GO :0042803: protein homodimerization activity, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005089: Rho guanyl-nucleotide exchange factor activity, this GO :0005096: GTPase activator activity, this GO :0005515: protein binding, this GO :0017048: Rho GTPase binding, this GO :0042803: protein homodimerization activity, 28366 and IDBG-636155 and ENSBTAG00000023814 and 100849477, 504746, epithelial cell transforming sequence 2 oncogene |
| Identity | 3155 |
| Gene | ECT2 |
| Long gene name | epithelial cell transforming 2 |
| Synonyms gene name | epithelial cell transforming sequence 2 oncogene |
| Synonyms | ARHGEF31 |
| Locus | 3q26, 31 |
| Discovery year | 1993-10-15 |
| GenBank acession | AA206473 |
| Entrez gene record | 1894 |
| Pubmed identfication | 8464478 10579713 |
| RefSeq identity | NM_018098 |
| Classification | Rho guanine nucleotide exchange factors |
| Havana BLAST/BLAT | OTTHUMG00000156762 |
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