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EDN3 Antibody

EDN3 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenEDN3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the EDN3 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis EDN3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P14138
PurityAntigen affinity
Description Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions, Four alternatively spliced transcript variants encoding three distinct isoforms have been observed, Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), The active form of this protein is a 21 amino acid peptide processed from the precursor protein, The active peptide is a ligand for endothelin receptor type B (EDNRB), The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons, which are congenital disorders involving neural crest-derived cells, The protein encoded by this gene is a member of the endothelin family
ImmunogenA portion of amino acids 168-197 from the human protein was used as the immunogen for this EDN3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the EDN3 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetEDN3
Short nameEDN3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameendothelin 3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target EDN3 and IDBG-641126 and ENSBTAG00000012109 and, EDN3 and IDBG-83422 and ENSG00000124205 and 1908, ET-3 and ET3 and HSCR4 and PPET3 and WS4B, Edn3 and IDBG-213499 and ENSMUSG00000027524 and 13616, Extracellular, hormone activity, this GO :0001755 and neural crest cell migration and biological process this GO :0002690 and positive regulation of leukocyte chemotaxis and biological process this GO :0003100 and regulation of systemic arterial blood pressure by endothelin and biological process this GO :0005102 and receptor binding and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008015 and blood circulation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0010460 and positive regulation of heart rate and biological process this GO :0014826 and vein smooth muscle contraction and biological process this GO :0019229 and regulation of vasoconstriction and biological process this GO :0030072 and peptide hormone secretion and biological process this GO :0030182 and neuron differentiation and biological process this GO :0030318 and melanocyte differentiation and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0042310 and vasoconstriction and biological process this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0046887 and positive regulation of hormone secretion and biological process this GO :0048016 and inositol phosphate-mediated signaling and biological process this GO :0048070 and regulation of developmental pigmentation and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005179: hormone activity, this GO :0005179: hormone activity, endothelin 3
Identity 3178
Gene EDN3
Long gene name endothelin 3
Synonyms ET3
Locus 20q13, 32
Discovery year 1989-09-06
GenBank acession X52001
Entrez gene record 1908
RefSeq identity NM_000114
Classification Endogenous ligands
Havana BLAST/BLAT OTTHUMG00000032867
Locus Specific Databases LOVD - Leiden Open Variation Database

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