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EIF2AK1 Antibody

EIF2AK1 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenEIF2AK1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ICC, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, Immunocytochemistry: 0, Western blot: 0
Notes Titration of the EIF2AK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis EIF2AK1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9BQI3
PurityAntigen affinity
Description Chen and London(1995) reviewed the activation and control of rat and rabbit EIF2AK1, Hartz(2010) mapped the gene to chromosome 7p22, Hwang et al, It functions as a dimer, Using cDNA arrays and Northern blot analysis, also called HRI, and its activation involves autophosphorylation, is an enzyme that in humans is encoded by the EIF2AK1 gene, which requires an invariant lysine in kinase domain II, (2000) found that EIF2AK1 was downregulated in the majority of ovarian cancers examined compared with normal ovarian tissues, 1 based on an alignment of the EIF2AK1 sequence with the genomic sequence, Eukaryotic Translation Initiation Factor 2-Alpha Kinase 1
ImmunogenAn amino acid sequence from the middle region of human Eukaryotic Translation Initiation Factor 2-Alpha Kinase 1 (CTDILQKNTDWTNRNGKR) was used as the immunogen for this EIF2AK1 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the EIF2AK1 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetEIF2AK1
Short nameEIF2AK1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEIF2AK1 (Antibody to)
Alternative techniqueantibodies
Identity 24921
Gene EIF2AK1
Long gene name eukaryotic translation initiation factor 2 alpha kinase 1
Synonyms HRI KIAA1369
Synonyms name heme regulated initiation factor 2 alpha kinase
Locus 7p22, 1
Discovery year 2005-01-19
GenBank acession BC006524
Entrez gene record 27102
Pubmed identfication 7709427 10718198
RefSeq identity NM_014413
Havana BLAST/BLAT OTTHUMG00000090689

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