Name : EIF2AK1 Antibody
Supplier : NJS POLY
Price :389
SKU : GEN5227576899
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | EIF2AK1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ICC, WB |
| Recommended dilutions | 5-1ug/ml, 5-1ug/ml, Immunocytochemistry: 0, Western blot: 0 |
| Notes | Titration of the EIF2AK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This EIF2AK1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9BQI3 |
| Purity | Antigen affinity |
| Description | Chen and London(1995) reviewed the activation and control of rat and rabbit EIF2AK1, Hartz(2010) mapped the gene to chromosome 7p22, Hwang et al, It functions as a dimer, Using cDNA arrays and Northern blot analysis, also called HRI, and its activation involves autophosphorylation, is an enzyme that in humans is encoded by the EIF2AK1 gene, which requires an invariant lysine in kinase domain II, (2000) found that EIF2AK1 was downregulated in the majority of ovarian cancers examined compared with normal ovarian tissues, 1 based on an alignment of the EIF2AK1 sequence with the genomic sequence, Eukaryotic Translation Initiation Factor 2-Alpha Kinase 1 |
| Immunogen | An amino acid sequence from the middle region of human Eukaryotic Translation Initiation Factor 2-Alpha Kinase 1 (CTDILQKNTDWTNRNGKR) was used as the immunogen for this EIF2AK1 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the EIF2AK1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | EIF2AK1 |
| Short name | EIF2AK1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | EIF2AK1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24921 |
| Gene | EIF2AK1 |
| Long gene name | eukaryotic translation initiation factor 2 alpha kinase 1 |
| Synonyms | HRI KIAA1369 |
| Synonyms name | heme regulated initiation factor 2 alpha kinase |
| Locus | 7p22, 1 |
| Discovery year | 2005-01-19 |
| GenBank acession | BC006524 |
| Entrez gene record | 27102 |
| Pubmed identfication | 7709427 10718198 |
| RefSeq identity | NM_014413 |
| Havana BLAST/BLAT | OTTHUMG00000090689 |