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EML4 Antibody, Biotin Conjugated

EML4 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, EML4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEML4
SpecificityThis is a highly specific antibody against EML4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human EML4/C2orf180
Gene ID number27436
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background C2orf2 or ROPP120, Due to a chromosomal inversion with chromosome 2p, ELP120, EML4 (Echinoderm microtubule-associated protein-like 4), EML4 is thought to modify the assembly dynamics of microtubules, EML4 may exist as a fusion protein with ALK (anaplastic lymphoma receptor tyrosine kinase), Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules, Expressed at high levels during mitosis, also known as EMAPL4, cell motility, is a 981 amino acid cytoplasmic protein that contains nine WD repeats, producing an EML4-ALK fusion complex that plays a role in the pathogenesis of lung cancer, specifically altering microtubules to become longer and more flexible, spindle formation and chromosome movements, Microtubules are components of the Actin cytoskeleton that play crucial roles in cell morphogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms ROPP120 ELP120
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetEML4 Conjugated
Short name Conjugated, EML4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, EML4 (Antibody to)
Alternative techniqueantibodies
Identity 1316
Gene EML4
Long gene name echinoderm microtubule associated protein like 4
Synonyms gene C2orf2
Locus 2p21
Discovery year 2000-01-31
GenBank acession AF177377
Entrez gene record 27436
RefSeq identity NM_019063
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000128603

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