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Ep300 Antibody

Ep300 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameEp300 Primary Polyclonal Antibody
Also known asEp300 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEp300
SpecificityThis is a highly specific antibody against Ep300
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EP300 inhibitory protein 1
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Another high molecular weight transcriptional adapter protein, It has been shown that protein kinase A-mediated CREB phosphorylation results in its binding to a nuclear protein designated CBP (for CREB-binding protein), Many transcription factors bind to this element, Sequence analysis of CBP and p300 has revealed substantial homology, These findings suggest that CBP has many of the properties expected of a CREB co-activator, arguing that these proteins are members of a conserved family of co-activators, designated p300, including the protein CREB which is activated as a result of phosphorylation by protein kinase A, is characterized by three cysteine- and histidine-rich regions, of which the most carboxy terminal region specifically binds the adenovirus E1A protein, p300 molecules lacking an intact E1A binding site bypass E1A repression even in the presence of high concentrations of E1A, Cyclic AMP-regulated gene expression frequently involves a DNA element designated the cAMP-regulated enhancer (CRE)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 300 HAT, Cyclic AMP responsive enhancer binding protein, E1A associated protein p300, E1A binding protein p300, E1A-associated protein p300, EC 2, EP300, EP300: E1A binding protein p300, EP300_HUMAN, RB and P300 binding protein EID 1, RSTS2, Retinoblastoma protein associated protein, istone acetyltransferase p300, 1, 3, 48, CREBBP/EP300 inhibitory protein 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetEp300
Short nameEp300 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameE1A binding protein p300 (Antibody to)
Alternative techniqueantibodies
Identity 50504
Gene EP300-AS1
Long gene name EP300 antisense RNA 1
Locus 22q13, 2
Discovery year 2014-05-12
Entrez gene record 101927279
Havana BLAST/BLAT OTTHUMG00000150941

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