Name : Ep300 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6287304615
| Long name | Ep300 Primary Polyclonal Antibody |
| Also known as | Ep300 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Ep300 |
| Specificity | This is a highly specific antibody against Ep300 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EP300 inhibitory protein 1 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Another high molecular weight transcriptional adapter protein, It has been shown that protein kinase A-mediated CREB phosphorylation results in its binding to a nuclear protein designated CBP (for CREB-binding protein), Many transcription factors bind to this element, Sequence analysis of CBP and p300 has revealed substantial homology, These findings suggest that CBP has many of the properties expected of a CREB co-activator, arguing that these proteins are members of a conserved family of co-activators, designated p300, including the protein CREB which is activated as a result of phosphorylation by protein kinase A, is characterized by three cysteine- and histidine-rich regions, of which the most carboxy terminal region specifically binds the adenovirus E1A protein, p300 molecules lacking an intact E1A binding site bypass E1A repression even in the presence of high concentrations of E1A, Cyclic AMP-regulated gene expression frequently involves a DNA element designated the cAMP-regulated enhancer (CRE) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 300 HAT, Cyclic AMP responsive enhancer binding protein, E1A associated protein p300, E1A binding protein p300, E1A-associated protein p300, EC 2, EP300, EP300: E1A binding protein p300, EP300_HUMAN, RB and P300 binding protein EID 1, RSTS2, Retinoblastoma protein associated protein, istone acetyltransferase p300, 1, 3, 48, CREBBP/EP300 inhibitory protein 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Ep300 |
| Short name | Ep300 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | E1A binding protein p300 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 50504 |
| Gene | EP300-AS1 |
| Long gene name | EP300 antisense RNA 1 |
| Locus | 22q13, 2 |
| Discovery year | 2014-05-12 |
| Entrez gene record | 101927279 |
| Havana BLAST/BLAT | OTTHUMG00000150941 |