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Eph receptor A3 Antibody

Eph receptor A3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEph receptor A3 Primary Polyclonal Antibody
Also known asEph receptor A3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEph receptor A3
SpecificityThis is a highly specific antibody against Eph receptor A3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range430-465/983
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Eph receptor A3
Gene ID number2042
Swiss ProtP29320
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5, Involved in the retinotectal mapping of neurons, May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development, Plays a role in cardiac cells migration and differentiation and regulates the formation of the atrioventricular canal and septum during development probably through activation by EFNA1, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration, leading to contact-dependent bidirectional signaling into neighboring cells, Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names EPH-like kinase 4, EPHA3, ETK, ETK1, Eph-like tyrosine kinase 1, Ephrin type-A receptor 3, HEK, HEK4, Human embryo kinase, TYRO4, Tyrosine-protein kinase TYRO4, Tyrosine-protein kinase receptor ETK1, EK4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetEph receptor A3
Short nameEph receptor A3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEph receptor A3 (Antibody to)
Alternative techniqueantibodies
Identity 3484
Gene ETK1
Long gene name EPH receptor A3
Synonyms gene ETK TYRO4
Synonyms gene name EphA3
Synonyms HEK HEK4 EPHA3
Locus 3p11, 1
Discovery year 1993-06-23
GenBank acession M83941
Entrez gene record 2042
Pubmed identfication 1737782 1311845
RefSeq identity NM_005233
Classification Sterile alpha motif domain containing Fibronectin type III domain containing EPH receptors
Havana BLAST/BLAT OTTHUMG00000159040

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