Filters

EphA2 (Tyr594) Antibody

EphA2 (Tyr594) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEphA2 (Tyr594) Primary Polyclonal Antibody
Also known asEphA2 (Tyr594) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEphA2 Tyr594
Specificity Due to the highly conserved nature of this protein to EphA4 and EphA5, This phosphorylation site is homologous to Tyr595 in Mouse and Rat, Tyr495 in Mouse, and Tyr658 in Rat, mu, rt) and EphA5 when phosphorylated at Tyr656 in Human, this antibody may react with these EphA4 when phosphorylated at Tyr602 (hu, This is a highly specific antibody against EphA2 Tyr594
Modification(s)Phosphorylation
Modification site(s)Tyr594
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range570-610/976
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human EphA2 around the phosphorylation site of Tyr594
Gene ID number1969
Swiss ProtP29317
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activated by the ligand ephrin-A1/EFNA1 regulates migration, During development, Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance, Involved for instance in angiogenesis, May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration, Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development, integrin-mediated adhesion, leading to contact-dependent bidirectional signaling into neighboring cells, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues, proliferation and differentiation of cells, respectively) signaling pathway, Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ARCC2, CTPA, CTPP1, CTRCT6, EPHA2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, ECK
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetEphA2 (Tyr594)
Short nameEphA2 (Tyr594) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEPH receptor A2 (Tyr594) (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter