Name : EPLIN Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8507033375
| Long name | EPLIN Primary Polyclonal Antibody |
| Also known as | EPLIN PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | EPLIN |
| Specificity | This is a highly specific antibody against EPLIN |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EPLIN |
| Gene ID number | 51474 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | By binding Actin monomers and filaments, Downregulation of EPLIN-Î, EPLIN is involved in regulation of the Actin cytoskeleton by increasing the number and size of Actin stress fibers, EPLIN is strongly expressed in placenta, EPLIN-Î, It also contains at least two Actin-binding domains, It also inhibits membrane ruffling and Actin filament depolymerization, It is expressed as two isoforms, and EPLIN-Î, and to a lesser degree in lung, brain, delaying filament nucleation, expression may contribute to the motility of invasive tumor cells, in which the C-terminal domain binds more effectively than the N-terminal domain, isl-1 and mec-3 (LIM) domain, kidney, liver, ovary, pancreas, prostate, reducing formation of branched filaments and bundling of Actin filaments, skeletal muscle, spleen and heart, testis and intestine, thymus, ±, ±, ², Epithelial protein lost in neoplasm (EPLIN) is a cytoskeleton-associated protein characterized by the presence of a single centrally located lin-11 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | EPLIN, Epithelial protein lost in neoplasm, Epithelial protein lost in neoplasm beta, FLJ38853, LIM domain and actin binding 1, LIM domain and actin binding protein 1, LIM domain and actin-binding protein 1, LIMA1, LIMA1_HUMAN, MGC131726, SREBP3, Sterol regulatory element binding protein 3, 1110021C24Rik |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | EPLIN |
| Short name | EPLIN Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | EPLIN (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24636 |
| Gene | LIMA1 |
| Long gene name | LIM domain and actin binding 1 |
| Synonyms | EPLIN |
| Synonyms name | epithelial protein lost in neoplasm beta |
| Locus | 12q13, 12 |
| Discovery year | 2006-02-22 |
| GenBank acession | AF198454 |
| Entrez gene record | 51474 |
| Pubmed identfication | 10806352 10618726 12566430 |
| RefSeq identity | NM_016357 |
| Classification | LIM domain containing |
| Havana BLAST/BLAT | OTTHUMG00000169852 |