Name : ERN2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3297615131
| Long name | ERN2 Primary Polyclonal Antibody |
| Also known as | ERN2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ERN2 |
| Specificity | This is a highly specific antibody against ERN2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ERN2 |
| Gene ID number | 10595 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | It is pro-apoptotic and appears to play no role in the unfolded-protein response, endoplasmic reticulum to nucleus signaling 2, induces translational repression through 28S ribosomal RNA cleavage in response to ER stress, unlike closely related proteins, ERN2 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ER to nucleus signalling 2, ERN 2, ERN2_HUMAN, Endoplasmic reticulum to nucleus signaling 2, Ern1, IRE1 S, IRE2, Inositol requiring 1 beta, Inositol requiring protein 2, Ire1, Ire1 beta, Serine/threonine protein kinase/endoribonuclease IRE2, cerevisiae homolog of, hIRE2p, IRE1b |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ERN2 |
| Short name | ERN2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | endoplasmic reticulum to nucleus signaling 2 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006397 and mRNA processing and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016075 and rRNA catabolic process and biological process this GO :0016772 and transferase activity, DNA-templated and biological process this GO :0070059 and intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process this GO :0090305 and nucleic acid phosphodiester bond hydrolysis and biological process this GO :0090501 and RNA phosphodiester bond hydrolysis and biological process, ERN2 and IDBG-20788 and ENSG00000134398 and 10595, ERN2 and IDBG-638556 and ENSBTAG00000014456 and 508486, Ern2 and IDBG-208930 and ENSMUSG00000030866 and 26918, IRE1-BETA and IRE1b, Plasma membranes, this GO :0000287 and magnesium ion binding and molecular function this GO :0004519 and endonuclease activity and molecular function this GO :0004540 and ribonuclease activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006351 and transcription, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0004519: endonuclease activity and also this GO :0004540: ribonuclease activity and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004519: endonuclease activity, this GO :0004540: ribonuclease activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0030263 and apoptotic chromosome condensation and biological process this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0045892 and negative regulation of transcription, endoplasmic reticulum to nucleus signaling 2 |
| Identity | 16942 |
| Gene | ERN2 |
| Long gene name | endoplasmic reticulum to nucleus signaling 2 |
| Synonyms gene name | ER to nucleus signalling 2 |
| Synonyms | IRE1b |
| Locus | 16p12, 2 |
| Discovery year | 2003-01-27 |
| GenBank acession | AA527544 |
| Entrez gene record | 10595 |
| Pubmed identfication | 9755171 11175748 |
| Havana BLAST/BLAT | OTTHUMG00000177020 |