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Escherichia coli O17:K52:H18 LPS-assembly lipoprotein lptE (lptE)

Escherichia coli O17:K52:H18 LPS-assembly lipoprotein lptE (lptE) size: 100ug 1564

Supplier MBS RECOMBINANT PROTEINS
Price 1564
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRecombinant Escherichia coli O17:K52:H18 LPS-assembly lipoprotein lptE (lptE)
Alternative names LPS-assembly lipoprotein LptE, LPS-assembly lipoprotein RlpB, LPS-assembly lipoprotein RlpB
Gene namelptE
Other gene names ECUMN_0735, lptE, rlpB, rlpB
General description All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, LPS-assembly lipoprotein lptE (lptE) is a recombinant protein expressed in Baculovirus
Product categoryRecombinant Proteins
Expression systemBaculovirus
Available also expressed in: Baculovirus , Mammalian Cell, Yeast , E Coli
PurityGreater than 90% (determined by SDS-PAGE)
FormLyophilized protein
Storage Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius
Applications IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA
Gene According to the current model, Agonistic forms of LPS or lipid A trigger numerous physiological immunostimulatory effects in mammalian organisms, Cells of the myeloid lineage have been shown to be the primary cellular sensors for LPS in the mammalian immune system, During the past decade, In addition, LPS consist of a poly- or oligosaccharide region that is anchored in the outer bacterial membrane by a specific carbohydrate lipid moiety termed lipid A, Some members of the latter more heterogeneous group are capable of antagonizing the effects of strongly stimulatory LPS/lipid A forms, The elucidation of structure-activity correlations in LPS and lipid A has not only contributed to a molecular understanding of both immunostimulatory and toxic septic processes, The lipid A component is the primary immunostimulatory center of LPS, With respect to immunoactivation in mammalian systems, but has also re-animated the development of new pharmacological and immuno-stimulatory strategies for the prevention and therapy of infectious and malignant diseases, but--in higher doses--can also lead to pathological reactions such as the induction of septic shock, enormous progress has been obtained in the elucidation of the central LPS/lipid A recognition and signaling system in mammalian phagocytes, leading to the rapid activation of an intracellular signaling network that is highly homologous to the signaling systems of IL-1 and IL-18, several natural or derivative lipid A structures have been identified that display comparatively low or even no immunostimulation for a given mammalian species, the classical group of strongly agonistic (highly endotoxin) forms of LPS has been shown to be comprised of a rather similar set of lipid A types, the membrane-bound or soluble forms of CD14 and the newly identified Toll-like receptor 4 (TLR4)*MD-2 complex, the specific cellular recognition of agonistic LPS/lipid A is initialized by the combined extracellular actions of LPS binding protein (LBP), Bacterial pathogen lipopolysaccharides (LPS) are the major outer surface membrane components present in almost all Gram-negative bacteria and act as extremely strong stimulators of innate or natural immunity in diverse eukaryotic species ranging from insects to humans
Gene targetEscherichia coli O17:K52:H18 LPS-assembly lipoprotein lptE (lptE)
Short nameEscherichia coli O17:K52:H18 LPS-assembly lipoprotein lptE (lptE)
HostEscherichia coli
Alternative nameEscherichia coli O17:K52:H18 LPS-assembly lipoprotein lptE (lptE)
Alternative techniqueescherichia

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