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EXOSC10/PMSCL2 Antibody, FITC Conjugated

EXOSC10/PMSCL2 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, EXOSC10/PMSCL2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEXOSC10/PMSCL2
SpecificityThis is a highly specific antibody against EXOSC10/PMSCL2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human EXOSC10/PMSCL2
Gene ID number5394
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background EXOSC10, EXOSC10 is part of the post-splicing exosome complex and is involved in mRNA surveillance, Localized to both the cytoplasm and the nucleus, PM-Scl, PMSCL2, RRP6, Rrp6p, The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3â, Two isoforms of EXOSC10 exist due to alternative splicing events, against EXOSC10 have been found in patients with scleroderma and/or polymyositis (chronic diseases of the skin and muscle, also known as PMSCL, enonuclease domain, exoribonucleases, is an 885 amino acid protein that contains one HRDC domain and one 3â, mRNA nuclear export and nonsense-mediated decay of mRNAs containing premature stop codons, or PM/Scl-100, p2, p3, p4, region, respectively), some of which are 3â, suggesting that EXOSC10 may be involved in the pathogenesis of these diseases, to 5â, &euro, &euro, &euro, &euro, &euro, &trade, &trade, &trade, &trade, &trade, -5â, The exosome is a multi-subunit complex composed of several highly conserved proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms PM-Scl PM/Scl-100 Rrp6p RRP6 p2 p3 p4
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetEXOSC10/PMSCL2 Conjugated
Short name FITC Conjugated, EXOSC10/PMSCL2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, EXOSC10/PMSCL2 (Antibody to)
Alternative techniqueantibodies
Identity 9138
Gene EXOSC10
Long gene name exosome component 10
Synonyms gene PMSCL2
Synonyms gene name 100kDa , polymyositis/scleroderma autoantigen 2
Synonyms name polymyositis/scleroderma autoantigen 2 (100kD)
Locus 1p36, 22
Discovery year 1994-09-19
GenBank acession BC073788
Entrez gene record 5394
Pubmed identfication 1383382 1644924
RefSeq identity NM_001001998
Classification Exosome complex
Havana BLAST/BLAT OTTHUMG00000002123

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