Name : FASP1 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8289911776
| Long name | Biotin Conjugated, FASP1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FASP1 |
| Specificity | This is a highly specific antibody against FASP1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human FASP1/C21orf45 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | FASP1, FASP1 exists as a homodimer, FASP1 has been shown to bind to pp5644 in Hela cells, In yeast, Mis18 is localized to the centrosome and forms a complex with Mis16 to maintain the deacetylated state of histones specifically in the central core of centromeres, With expression in testis, a heterodimer with MIS18B or is present in a complex containing other Mis18 family members, also known as Protein Mis18-alpha and C21orf45, is required for the recruitment of CENP-A to centrosomes and is thereby essential for normal chromosome segregation during mitosis, the FASP1 gene (FAPP1-associated protein 1) encodes a 233 amino acid protein that is homologous to the fission yeast protein Mis18, where overexpression of pp5644 leads to inhibited growth and colony formation, Mapping to chromosome 21 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | B28 FASP1 hMis18alpha |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FASP1 Conjugated |
| Short name | Conjugated, FASP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, FASP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1286 |
| Gene | MIS18A |
| Long gene name | MIS18 kinetochore protein A |
| Synonyms gene | C21orf46 C21orf45 |
| Synonyms gene name | chromosome 21 open reading frame 46 chromosome 21 open reading frame 45 MIS18 kinetochore protein homolog A (S, pombe) |
| Locus | 21q22, 11 |
| Discovery year | 2000-05-23 |
| GenBank acession | AF231921 |
| Entrez gene record | 54069 |
| Pubmed identfication | 17199038 |
| RefSeq identity | NM_018944 |
| Havana BLAST/BLAT | OTTHUMG00000085308 |