Name : Fibrillin 2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3362236914
| Long name | Fibrillin 2 Primary Polyclonal Antibody |
| Also known as | Fibrillin 2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Fibrillin 2 |
| Specificity | This is a highly specific antibody against Fibrillin 2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrillin 2 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Epithelial cells primarily deposit fibrillin into the extracellular matrix in a nonfibrillar form, Fibrillin-2 constitutes the backbone of microfibrils which insert directly into the lamina densa of basement membranes, Fibrillin-2 containing microfibrils regulate the early process of elastic fiber assembly in tissue, Mutations in the 8-cysteine motif of Fibrillin-2 alters its binding to microfibril-associated glycoprotein-1 (MAGP-1), Mutations in the fibrillin-2 gene resulting in impaired assembly of fibrillin-2 may lead to molecular congenital contractural arachnodactyly, which may increase the severity of congenital contractural arachnodactyly, Extracellular glycoproteins fibrillin-1 and -2 are major components of connective tissue microfibrils |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DA9, FBN2, FBN2_HUMAN, Fibrillin-2, congenital contractural arachnodactyly Marfanoid-like, fibrillin 2 congenital contractural arachnodactyly, CCA |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Fibrillin 2 |
| Short name | Fibrillin 2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Fibrillin 2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3604 |
| Gene | FBN2 |
| Long gene name | fibrillin 2 |
| Synonyms gene | CCA |
| Synonyms gene name | congenital contractural arachnodactyly |
| Synonyms | DA9 |
| Synonyms name | fibrillin 5 |
| Locus | 5q23, 3 |
| Discovery year | 1991-08-21 |
| GenBank acession | U03272 |
| Entrez gene record | 2201 |
| Pubmed identfication | 1852206 8120105 |
| RefSeq identity | NM_001999 |
| Havana BLAST/BLAT | OTTHUMG00000163082 |