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FOG2 Antibody

FOG2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFOG2 Primary Polyclonal Antibody
Also known asFOG2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFOG2
SpecificityThis is a highly specific antibody against FOG2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FOG2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen FOG-2 inhibits GATA-4 transcriptional activity, FOG-2 is able to both positively and negatively influence GATA mediated transcription, FOG-2 is predominantly expressed in heart, FOG/GATA-1 complexes are required for erythroid and megakaryocyte maturation, GATA-4 and GATA-6, In cardiomyocytes and fibroblasts, These complexes involve the association between multiple zinc fingers on the FOG proteins and the N-terminal zinc finger of GATA proteins, While FOG cooperatively regulates GATA-1 induced transcription, and it preferentially participates in the regulation of GATA-3, and they promote differentiation during embryonic development, are zinc finger proteins that interact with the GATA family of transcriptional regulators, including FOG (friend of GATA-1) and FOG-2, neurons and gonads, suggesting that the observed effects of FOG-2 are context specific and vary between cellular systems, yet FOG-2 restores GATA-1 mediated transcription in erythroid cultures deficient in FOG, The FOG family of transcriptional cofactors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FOG2_HUMAN, Friend of GATA 2, Friend of GATA protein 2, Friend of GATA2 , ZFPM2, Zinc finger protein 89B, Zinc finger protein M2, Zinc finger protein ZFPM2, Zinc finger protein multitype 2 , hFOG-2 , FOG-2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFOG2
Short nameFOG2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFOG2 (Antibody to)
Alternative techniqueantibodies
Identity 16700
Gene ZFPM2
Long gene name FOG family member 2 , zinc finger protein
Synonyms gene name multitype 2 , zinc finger protein
Synonyms FOG2 hFOG-2 ZNF89B ZC2HC11B
Locus 8q23
Discovery year 2002-11-26
GenBank acession AF119334
Entrez gene record 23414
Pubmed identfication 9927675 10438528
Classification Zinc fingers C2H2-type Zinc fingers C2HC-type
Havana BLAST/BLAT OTTHUMG00000164818

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