Name : FosB Antibody
Supplier : NJS POLY
Price :389
SKU : GEN6720351737
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | FosB |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Notes | Titration of the FosB antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This FosB antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P53539 |
| Purity | Antigen affinity |
| Description | Delta FOSB is a truncated splice variant of FOSB, FOSB, FOSL1, It also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage, It has been implicated in the development of drug addiction and control of the reward system in the brain, It is a member of Fos gene family which consists of 4 members: FOS, The proteins have been implicated as regulators of cell proliferation, and FOSL2, and is linked to changes in a number of other gene products such as CREB and sirtuins, and transformation, differentiation, FBJ murine osteosarcoma viral oncogene homolog B is a protein that in humans is encoded by the FOSB gene |
| Immunogen | mouse and rat), An amino acid sequence from the N-terminus of human FosB (MFQAFPGDYDSGSRC) was used as the immunogen for this FosB antibody (100% homologous in human |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FosB antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | FosB |
| Short name | FosB Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | FosB (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3797 |
| Gene | FOSB |
| Long gene name | AP-1 transcription factor subunit , FosB proto-oncogene |
| Synonyms gene name | FBJ murine osteosarcoma viral oncogene homolog B |
| Synonyms | G0S3 GOSB GOS3 AP-1 MGC42291 DKFZp686C0818 |
| Synonyms name | oncogene FOS-B activator protein 1 |
| Locus | 19q13, 32 |
| Discovery year | 1992-09-18 |
| Entrez gene record | 2354 |
| Pubmed identfication | 1301997 |
| RefSeq identity | NM_006732 |
| Classification | Fos transcription factor family Basic leucine zipper proteins |
| Havana BLAST/BLAT | OTTHUMG00000182122 |