FoxO1 (Ser319) Antibody

FoxO1 (Ser319) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 281

Size 0.1ml

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Long name	FoxO1 (Ser319) Primary Polyclonal Antibody
Also known as	FoxO1 (Ser319) PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	FoxO1 Ser319
Specificity	Ser313 in rat, This phosphorylation site is found at Ser316 in mouse, This is a highly specific antibody against FoxO1 Ser319
Modification(s)	Phosphorylation
Modification site(s)	Ser319
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen range	315-325/655
Subcellular location	Nucleus, Cytoplasm
Source	KLH conjugated synthetic phosphopeptide derived from human FoxO1 around the phosphorylation site of Ser319 [TS(p-S)NA]
Gene ID number	2308
Swiss Prot	Q12778
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Activity suppressed by insulin, Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, Also suppresses the transcriptional activity of RUNX2, Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3', G6PC and PCK1, Important regulator of cell death acting downstream of CDK1, In hepatocytes, Main regulator of redox balance and osteoblast numbers and controls bone mass, Mediates insulin action on adipose tissue, Orchestrates the endocrine function of the skeleton in regulating glucose metabolism, PKB/AKT1 and SKT4/MST1, Promotes neural cell death, Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells, Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake, an upstream activator of osteocalcin/BGLAP, increasing glucose levels and triggering glucose intolerance and insulin insensitivity, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	FKHR, FOXO1, FOXO1A, Forkhead box protein O1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, FKH1
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	FoxO1 (Ser319)
Short name	FoxO1 (Ser319) Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	forkhead box O1 (Ser319) (Antibody to)
Alternative technique	antibodies

FoxO1 (Ser319) Antibody

FoxO1 (Ser319) Antibody size: 0.1ml 281

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