Name : FoxO3a (Ser318 + Ser321) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN8326104666
| Long name | FoxO3a (Ser318 + Ser321) Antibody |
| Also known as | FoxO3a (Ser318 + Ser321) Antibody |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | FoxO3a Ser318 + Ser321 |
| Specificity | Due to the highly conserved nature of this sequence, Ser319 and Ser322 in Mouse, These phosphorylation sites are homologous to Ser317 + Ser320 in Mouse and Rat, and Ser316 and Ser319 in Rat, there is a chance that this antibody will react with FoxO1a when phosphorylated at the the sites of Ser322 and Ser325 in Human, This is a highly specific antibody against FoxO3a Ser318 + Ser321 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser318 + Ser321 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 290-340/673 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human FoxO3a around the phosphorylation site of Ser318/321 |
| Gene ID number | 2309 |
| Swiss Prot | O43524 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation, Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3', including neuronal cell death upon oxidative stress, promotes induction of miR-34b and miR-34c expression, Transcriptional activator which triggers apoptosis in the absence of survival factors |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AF6q21, AF6q21 protein, FKHRL1, FKHRL1P2, FOXO3, FOXO3A, Forkhead box protein O3, Forkhead in rhabdomyosarcoma-like 1, FOXO2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FoxO3a (Ser318 + Ser321) |
| Short name | FoxO3a (Ser318 + Ser321) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | FoxO3a (Ser318 and Ser321) (Antibody to) |
| Alternative technique | antibodies |