| Long name | ALEXA FLUOR 488 Conjugated, FOXO4/FOXO1 (Ser197/Ser256) Antibody |
| Also known as | Anti-FOXO4/FOXO1 Ser197/Ser256 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FOXO4/FOXO1 Ser197/Ser256 |
| Specificity | This is a highly specific antibody against FOXO4/FOXO1 Ser197/Ser256 |
| Modification | Phosphorylation |
| Modification Site | Ser197/Ser256 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human FOXO4 around the phosphorylation site of Ser197 |
| Gene ID Number | 4303 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, Jan 2010], Multiple transcript variants encoding different isoforms have been found for this gene, Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes, [provided by RefSeq, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia, This gene encodes a member of the O class of winged helix/forkhead transcription factor family |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | AFX1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the FOXO4/FOXO1 (Ser197/Ser256) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | FOXO4/FOXO1 (Ser197/Ser256) |
| Short name | FOXO4/FOXO1 (Ser197/Ser256) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, FOXO4/forkhead box O1 (Ser197/Ser256) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006473 and protein acetylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009267 and cellular response to starvation and biological process this GO :0010508 and positive regulation of autophagy and biological process this GO :0031018 and endocrine pancreas development and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0032873 and negative regulation of stress-activated MAPK cascade and biological process this GO :0034599 and cellular response to oxidative stress and biological process this GO :0035947 and regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045599 and negative regulation of fat cell differentiation and biological process this GO :0045722 and positive regulation of gluconeogenesis and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0051721 and protein phosphatase 2A binding and molecular function this GO :0070417 and cellular response to cold and biological process this GO :0071455 and cellular response to hyperoxia and biological process this GO :0071732 and cellular response to nitric oxide and biological process this GO :2000505 and regulation of energy homeostasis and biological process, FKH1 and FKHR and FOXO1A, FOXO1 and IDBG-26475 and ENSG00000150907 and 2308, FOXO1 and IDBG-629639 and ENSBTAG00000044105 and 506618, Foxo1 and IDBG-143370 and ENSMUSG00000044167 and 56458, nuclei, protein phosphatase 2A binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000989 and transcription factor binding transcription factor activity and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001568 and blood vessel development and biological process this GO :0001659 and temperature homeostasis and biological process this GO :0001678 and cellular glucose homeostasis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000989: transcription factor binding transcription factor activity, this GO :0000989: transcription factor binding transcription factor activity and also this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0051721: protein phosphatase 2A binding, this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0043565: sequence-specific DNA binding, this GO :0051721: protein phosphatase 2A binding, forkhead box O1 |
| Identity | 7139 |
| Gene | FOXO4 |
| Long gene name | forkhead box O4 |
| Synonyms gene | MLLT7 |
| Synonyms gene name | 7 , 7 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog), translocated to, translocated to |
| Locus | Xq13, 1 |
| Discovery year | 1994-12-14 |
| Entrez gene record | 4303 |
| Pubmed identfication | 7529552 |
| RefSeq identity | NM_005938 |
| Classification | Forkhead boxes |
| Havana BLAST/BLAT | OTTHUMG00000021789 |
| Locus Specific Databases | Mental Retardation database |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue