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Frizzled 9/CD349 Antibody, Biotin Conjugated

Frizzled 9/CD349 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Frizzled 9/CD349 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFrizzled 9/CD349
Specificity This antibody may have slight cross reactivity with Frizzled 10, This is a highly specific antibody against Frizzled 9/CD349
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range180-229/591
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human Frizzled 9/CD349
Gene ID number8326
Swiss ProtO00144
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes, which leads to the activation of disheveled proteins, Receptor for Wnt proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FZD3 CD349
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFrizzled 9/CD349 Conjugated
Short name Conjugated, Frizzled 9/CD349 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Frizzled 9/CD349 (Antibody to)
Alternative techniqueantibodies
Identity 4047
Gene FZD9
Long gene name frizzled class receptor 9
Synonyms gene name frizzled (Drosophila) homolog 9 frizzled homolog 9 (Drosophila) frizzled 9, seven transmembrane spanning receptor frizzled family receptor 9
Locus 7q11, 23
Discovery year 1998-09-17
GenBank acession U82169
Entrez gene record 8326
Pubmed identfication 9147651 10198163
Classification Class F frizzled CD molecules , G protein-coupled receptors
Havana BLAST/BLAT OTTHUMG00000023051

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