Name : GAB2 (Ser159) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN7323728112
| Long name | GAB2 (Ser159) Primary Polyclonal Antibody |
| Also known as | GAB2 (Ser159) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GAB2 Ser159 |
| Specificity | This is a highly specific antibody against GAB2 Ser159 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser159 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 130-170/676 |
| Source | KLH conjugated synthetic phosphopeptide derived from human GAB2 around the phosphorylation site of Ser159 |
| Gene ID number | 9846 |
| Swiss Prot | Q9UQC2 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Also involved in the regulation of cell proliferation and hematopoiesis, In allergic response, Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling, antigen, cell matrix and growth factor receptors to regulate multiple signaling pathways, hormone, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation, Adapter protein which acts downstream of several membrane receptors including cytokine |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | GAB2, GRB2-associated binder 2, Growth factor receptor bound protein 2-associated protein 2, KIAA0571, pp100, GRB2-associated-binding protein 2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GAB2 (Ser159) |
| Short name | GAB2 (Ser159) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GRB2-associated binding protein 2 (Ser159) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | GAB2 and IDBG-65975 and ENSG00000033327 and 9846, Plasma membranes, phosphatidylinositol-3, this GO :0005068 and transmembrane receptor protein tyrosine kinase adaptor activity and molecular function this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005547 and phosphatidylinositol-3, this GO :0005068: transmembrane receptor protein tyrosine kinase adaptor activity, this GO :0005068: transmembrane receptor protein tyrosine kinase adaptor activity and also this GO :0005070: SH3/SH2 adaptor activity and also this GO :0005515: protein binding and also this GO :0005547: phosphatidylinositol-3, this GO :0005070: SH3/SH2 adaptor activity, this GO :0005515: protein binding, this GO :0005547: phosphatidylinositol-3, this GO :0043325: phosphatidylinositol-3, 4, 4, 4, 4-bisphosphate binding, 4-bisphosphate binding, 4-bisphosphate binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process, 5-trisphosphate binding, 5-trisphosphate binding and also this GO :0043325: phosphatidylinositol-3, 5-trisphosphate binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043306 and positive regulation of mast cell degranulation and biological process this GO :0043325 and phosphatidylinositol-3, GRB2-associated binding protein 2 |
| Identity | 14458 |
| Gene | GAB2 |
| Long gene name | GRB2 associated binding protein 2 |
| Synonyms | KIAA0571 |
| Synonyms name | Grb2-associated binder 2 |
| Locus | 11q14, 1 |
| Discovery year | 2001-01-24 |
| GenBank acession | AB011143 |
| Entrez gene record | 9846 |
| Pubmed identfication | 10391903 10068651 |
| RefSeq identity | NM_080491 |
| Classification | Pleckstrin homology domain containing |
| Havana BLAST/BLAT | OTTHUMG00000166673 |