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GAB2 (Ser623) Antibody, ALEXA FLUOR 488

GAB2 (Ser623) Antibody, ALEXA FLUOR 488 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, GAB2 (Ser623) Polyclonal Antibody
Also known asAnti-GAB2 Ser623 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGAB2 Ser623
SpecificityThis is a highly specific antibody against GAB2 Ser623
ModificationPhosphorylation
Modification SiteSer623
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human GAB2 around the phosphorylation site of Ser623
Gene ID Number9846
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen CrkL and SHC, Gab2 acts as a docking protein for several SH2-containing proteins, Gab2 interacts with SHP2 tyrosine phosphatase and GRB2 adaptor protein PI3-kinase, Gab2 is a substrate of various RTKs, Upon tyrosine phosphorylation, cytokine receptors as well as B and T cell antigen receptors, growth factors and cytokines, including EGFR, insulin receptor, Gab2 (Grb2-associated binder-2) is an adaptor protein involved in numerous intracellular signaling pathways via its interaction with receptor tyrosine kinases (RTKs)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms KIAA0571
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GAB2 (Ser623) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetGAB2 (Ser623)
Short nameGAB2 (Ser623) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, GRB2-associated binding protein 2 (Ser623) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target GAB2 and IDBG-65975 and ENSG00000033327 and 9846, Plasma membranes, phosphatidylinositol-3, this GO :0005068 and transmembrane receptor protein tyrosine kinase adaptor activity and molecular function this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005547 and phosphatidylinositol-3, this GO :0005068: transmembrane receptor protein tyrosine kinase adaptor activity, this GO :0005068: transmembrane receptor protein tyrosine kinase adaptor activity and also this GO :0005070: SH3/SH2 adaptor activity and also this GO :0005515: protein binding and also this GO :0005547: phosphatidylinositol-3, this GO :0005070: SH3/SH2 adaptor activity, this GO :0005515: protein binding, this GO :0005547: phosphatidylinositol-3, this GO :0043325: phosphatidylinositol-3, 4, 4, 4, 4-bisphosphate binding, 4-bisphosphate binding, 4-bisphosphate binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process, 5-trisphosphate binding, 5-trisphosphate binding and also this GO :0043325: phosphatidylinositol-3, 5-trisphosphate binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043306 and positive regulation of mast cell degranulation and biological process this GO :0043325 and phosphatidylinositol-3, GRB2-associated binding protein 2
Identity 14458
Gene GAB2
Long gene name GRB2 associated binding protein 2
Synonyms name Grb2-associated binder 2
Locus 11q14, 1
Discovery year 2001-01-24
GenBank acession AB011143
Entrez gene record 9846
Pubmed identfication 10391903 10068651
RefSeq identity NM_080491
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000166673

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