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GAK Antibody

GAK Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenGAK
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB, IHC
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the GAK antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis GAK antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q6P490
PurityPurified
Description Expression is ubiquitous, Expression oscillates slightly during the cell cycle, GAK localizes to the perinuclear area and to the trans-Golgi network, It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells, It is also observed on the plasma membrane, The protein contains 1 J domain and 1 tensin domain, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5, peaking at G1, probably at focals adhesions, wiht highest levels in testis, GAK
ImmunogenA portion of amino acids 15-45 from the human protein was used as the immunogen for this GAK antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the GAK antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetGAK
Short nameGAK Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGAK (Antibody to)
Alternative techniqueantibodies
Identity 4113
Gene GAK
Long gene name cyclin G associated kinase
Synonyms DNAJC26
Synonyms name auxilin-2
Locus 4p16, 3
Discovery year 1997-01-09
GenBank acession D88435
Entrez gene record 2580
Pubmed identfication 9299234
RefSeq identity NM_005255
Classification DNAJ (HSP40) heat shock proteins C2 tensin-type domain containing
Havana BLAST/BLAT OTTHUMG00000088301

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