Name : GBA/Acid beta-glucosidase
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4631922696
| Long name | GBA/Acid beta-glucosidase |
| Also known as | GBA/Acid beta-glucosidase |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GBA/Acid beta-glucosidase |
| Specificity | This is a highly specific antibody against GBA/Acid beta-glucosidase |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Acid beta-glucosidase |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Beta-Glucosidase is used in enzyme replacement treatment aimed at treating Gaucher disease, Defects in Beta-Glucosidase cause Gaucher disease, The absorption of dietary flavonoid glycosides in humans involves a critical deglycosylation step that is mediated by epithelial Beta-glucosidases, an inherited condition distinguished by the accumulation of glucosylceramide within the cells of the reticuloendothelial system, Beta-Glucosidase is a predominantly liver enzyme which efficiently hydrolyzes Beta-D-glucoside and Beta-D-galactoside |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ACID, Acid beta-glucosidase, Alglucerase, BETA GLUCOSIDASE, Beta glucocerebrosidase, Beta-glucocerebrosidase, D glucosyl N acylsphingosine glucohydrolase, D-glucosyl-N-acylsphingosine glucohydrolase, EC 3, GBA, GBA1, GC antibody GCase, GCB, GLCM_HUMAN, GLUC, GLUCOCEREBROSIDASE PSEUDOGENE, Gba protein, Glucocerebrosidase, Glucocerebrosidase alt, Glucosidase, Glucosidase, Glucosidase beta, Glucosylceramidase, Imiglucerase, Lysosomal glucocerebrosidase, acid, acid includes glucosylceramidase, beta, beta, betaGC, 1, 2, 45 , Acid beta glucosidase |
| Gene target | GBA/Acid beta-glucosidase |
| Short name | GBA/Acid beta-glucosidase |
| Alternative name | GBA/Acid b-glucosidase |
| Identity | 4177 |
| Gene | GBA |
| Long gene name | glucosylceramidase beta |
| Synonyms gene | GLUC |
| Synonyms gene name | acid , acid (includes glucosylceramidase) glucosidase, beta, beta, glucosylceramidase glucosidase |
| Synonyms | GBA1 |
| Locus | 1q22 |
| Discovery year | 1986-01-01 |
| GenBank acession | M19285 |
| Entrez gene record | 2629 |
| Pubmed identfication | 3359914 |
| RefSeq identity | NM_000157 |
| Havana BLAST/BLAT | OTTHUMG00000035841 |