Name : GCNT2 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN7256471323
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | GCNT2 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IHC, WB |
| Recommended dilutions | IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the GCNT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This GCNT2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q06430 |
| Purity | Antigen affinity |
| Description | Alternatively spliced transcript variants encoding different isoforms have been described, Mutations in this gene have been associated with adult i blood group phenotype, The encoded protein is the I-branching enzyme, The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, a beta-1, respectively, 6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development, This gene encodes the enzyme responsible for formation of the blood group I antigen |
| Immunogen | A portion of amino acids 364-391 from the human protein was used as the immunogen for this GCNT2 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the GCNT2 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | GCNT2 |
| Short name | GCNT2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | I-branching enzyme (I blood family) (Antibody to), glucosaminyl (N-acetyl) transferase 2 |
| Alternative technique | antibodies |
| Alternative to gene target | BT, GCNT2 and IDBG-60908 and ENSG00000111846 and 2651, Gcnt2 and IDBG-146446 and ENSMUSG00000021360 and 14538, I-branching enzyme (I blood group), N-acetyllactosaminide beta-1, Plasma membranes, bA360O19, this GO :0000139 and this GO lgi membrane and cellular component this GO :0005575 and cellular component and cellular component this GO :0006024 and glycosaminoglycan biosynthetic process and biological process this GO :0006486 and protein glycosylation and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008109 and N-acetyllactosaminide beta-1, this GO :0008109: N-acetyllactosaminide beta-1, this GO :0008109: N-acetyllactosaminide beta-1, this GO :0008375: acetylglucosaminyltransferase activity, 1 and CCAT and CTRCT13 and GCNT2C and GCNT5 and IGNT and II and NACGT1 and NAGCT1 and ULG3, 2 and bA421M1, 38428 and IDBG-636273 and ENSBTAG00000039326 and 520336, 6-N-acetylglucosaminyltransferase activity, 6-N-acetylglucosaminyltransferase activity and also this GO :0008375: acetylglucosaminyltransferase activity, 6-N-acetylglucosaminyltransferase activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008375 and acetylglucosaminyltransferase activity and molecular function this GO :0010608 and posttranscriptional regulation of gene expression and biological process this GO :0010718 and positive regulation of epithelial to mesenchymal transition and biological process this GO :0010812 and negative regulation of cell-substrate adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030335 and positive regulation of cell migration and biological process this GO :0034116 and positive regulation of heterotypic cell-cell adhesion and biological process this GO :0036438 and maintenance of lens transparency and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process, glucosaminyl (N-acetyl) transferase 2 |
| Identity | 4204 |
| Gene | GCNT2 |
| Long gene name | I-branching enzyme (I blood group) , glucosaminyl (N-acetyl) transferase 2 |
| Synonyms gene | NACGT1 II GCNT5 CCAT |
| Synonyms gene name | I-branching enzyme (Ii blood group) cataract, I-branching enzyme glucosaminyl (N-acetyl) transferase 2, congenital , glucosaminyl (N-acetyl) transferase 5 glucosaminyl (N-acetyl) transferase 2 |
| Synonyms | IGNT NAGCT1 bA421M1, 1 bA360O19, 2 ULG3 |
| Synonyms name | Ii blood group unassigned linkage group 3 |
| Locus | 6p24, 2 , 3-p24 |
| Discovery year | 1993-09-07 |
| GenBank acession | L41605 |
| Entrez gene record | 2651 |
| Pubmed identfication | 8449405 9915862 |
| RefSeq identity | NM_145649 |
| Classification | Glucosaminyl (N-acetyl) transferases/xylosyltransferases Blood group antigens |
| Havana BLAST/BLAT | OTTHUMG00000014244 |
| Locus Specific Databases | LRG_819 |