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GCS1 Antibody, FITC Conjugated

GCS1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, GCS1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGCS1
SpecificityThis is a highly specific antibody against GCS1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GCS1
Gene ID number7841
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Glucosidase I catalyzes the first step in the N-linked oligosaccharide processing pathway, Glucosidase I contains a short cytosolic tail, It specifically removes the distal alpha 1, Mutations in the gene encoding Glucosidase I result in the congenital disorder glycosylation (CDG-IIb), Two point mutations in the Glucosidase I gene have been identified and result in amino acid substitutions, a single pass transmembrane domain and a large C-terminal catalytic domain located on the luminal side of the ER, dysmorphic features, feeding problems, hepatomegaly, hypoventilation, namely Arg486Thr and Phe652Leu, seizures and death, that affect polypeptide folding and active site formation, which is characterized by generalized hypotonia, 2-linked glucose residue from the Glc3-Man9-GlcNAc2 oligosaccharide precursor, Glycosylation of asparagine residues in Asn-X-Ser/Thr motifs in proteins commonly occur in the lumen of the endoplasmic reticulum (ER)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms GCS1 CWH41 DER7
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGCS1 Conjugated
Short name FITC Conjugated, GCS1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GCS1 (Antibody to)
Alternative techniqueantibodies
Identity 24862
Gene MOGS
Long gene name mannosyl-oligosaccharide glucosidase
Synonyms name glucosidase I processing A-glucosidase I
Locus 2p13, 1
Discovery year 2009-03-24
GenBank acession X87237
Entrez gene record 7841
Pubmed identfication 7635146 8786151
RefSeq identity NM_006302
Havana BLAST/BLAT OTTHUMG00000152886

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