Name : Gigaxonin Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN6133326273
| Long name | Cy3 Conjugated, Gigaxonin Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Gigaxonin |
| Specificity | This is a highly specific antibody against Gigaxonin |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human Gigaxonin |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | GAN1, Gigaxonin is a member of the cytoskeletal BTB/kelch repeat family and influences cytoskeletal organization and dynamics, Mutations in the Gigaxonin gene result in human giant axonal neuropathy (GAN), Overexpression of MAP1B may lead to neuronal cell death, The amino terminal BTB domain of gigaxonin binds to the ubiquitin-activating enzyme E1, also refered to as giant axonal neuropathy, an autosomal recessive neurodegenerative disorder characterized by axonal degeneration caused by cytoskeletal abnormalities, and tags it for degredation, controls protein degradation and is essential for neuronal function and survival, including accumulated intermediate filaments, or KLHL16, playing a large role in neurofilament architecture, whereas a reduction of MAP1B significantly improves the survival rate of neurons, while the carboxy-terminal kelch repeat domain interacts directly with the light chain of microtubule-associated protein 1B (MAP1B), Gigaxonin |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | GAN, GAN1, GAN_HUMAN, KLHL16, Kelch-like protein 16, giant axonal neuropathy, FLJ38059 |
| Properties | 1 of the Gigaxonin Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Gigaxonin Conjugated |
| Short name | Conjugated, Gigaxonin Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, Gigaxonin (Antibody to) |
| Alternative technique | antibodies |