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GIT1(Ser375) Antibody, ALEXA FLUOR 594

GIT1(Ser375) Antibody, ALEXA FLUOR 594 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, GIT1(Ser375) Polyclonal Antibody
Also known asAnti-GIT1 Ser375 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGIT1 Ser375
SpecificityThis is a highly specific antibody against GIT1 Ser375
ModificationPhosphorylation
Modification SiteSer375
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human GIT1 around the phosphorylation site of Ser375
Gene ID Number28964
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3, thus reducing b2-adrenergic receptor signaling (5), which are involved in vesicular trafficking (5, 2), 4), 6), Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetGIT1(Ser375)
Short nameGIT1(Ser375) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, GIT1(Ser375) (Antibody to)
Alternative techniqueantibodies
Identity 4272
Gene GIT1
Long gene name GIT ArfGAP 1
Synonyms gene name G protein-coupled receptor kinase interactor 1 G protein-coupled receptor kinase interacting ArfGAP 1
Locus 17q11, 2
Discovery year 2000-07-31
GenBank acession AF124490
Entrez gene record 28964
Pubmed identfication 9826657 10896954
RefSeq identity NM_014030
Classification Ankyrin repeat domain containing ArfGAPs
Havana BLAST/BLAT OTTHUMG00000132730

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