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GIT2 Antibody

GIT2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGIT2 Primary Polyclonal Antibody
Also known asGIT2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGIT2
SpecificityThis is a highly specific antibody against GIT2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GIT2
Gene ID number9815
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3, thus reducing b2-adrenergic receptor signaling (5), which are involved in vesicular trafficking (5, 2), 4), 6), Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ARF GTPase activating protein GIT2, ARF GTPase-activating protein GIT2, ARF GTPase-activating protein GIT2, CAT 2, CAT-2, CAT2, Cool associated tyrosine phosphorylated protein 2, Cool interacting tyrosine phosphorylated protein 2, Cool-interacting tyrosine-phosphorylated protein 2, Cool-interacting tyrosine-phosphorylated protein 2, DKFZp686G01261, G protein coupled receptor kinase interacting ArfGAP 2, G protein coupled receptor kinase interactor 2, G protein-coupled receptor kinase-interactor 2, G protein-coupled receptor kinase-interactor 2, GIT 2, GIT2, GIT2_HUMAN, GRK interacting protein 2, GRK-interacting protein 2, KIAA0148, MGC760, ARF GAP GIT2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGIT2
Short nameGIT2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGIT2 (Antibody to)
Alternative techniqueantibodies
Identity 4273
Gene GIT2
Long gene name GIT ArfGAP 2
Synonyms gene name G protein-coupled receptor kinase interactor 2 G protein-coupled receptor kinase interacting ArfGAP 2
Synonyms KIAA0148 PKL
Synonyms name Paxillin kinase linker
Locus 12q24, 11
Discovery year 2000-07-31
GenBank acession AF124491
Entrez gene record 9815
Pubmed identfication 9826657 10896954
RefSeq identity NM_057169
Classification Ankyrin repeat domain containing ArfGAPs
Havana BLAST/BLAT OTTHUMG00000169313

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