Filters

GLDC Antibody, Biotin Conjugated

GLDC Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, GLDC Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGLDC
SpecificityThis is a highly specific antibody against GLDC
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GLDC
Gene ID number2731
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background DLD (known as Protein L) and GLDC (known as Protein P), GCSH (known as Protein H), GCSP (glycine cleavage system P protein) or HYGN1, GLDC (glycine dehydrogenase ), GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T, GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor, Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), all of which work together to catalyze the cleavage and degradation of glycine, also known as GCE, also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms, is a 1, 020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family, The glycine cleavage system is comprised of AMT (known as Protein T)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms GCSP NKH
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGLDC Conjugated
Short name Conjugated, GLDC Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, GLDC (Antibody to)
Alternative techniqueantibodies
Identity 4313
Gene GLDC
Long gene name glycine decarboxylase
Synonyms gene name glycine cleavage system protein P) glycine dehydrogenase (decarboxylating) , glycine decarboxylase, glycine dehydrogenase (decarboxylating
Synonyms name glycine cleavage system protein P glycine dehydrogenase
Locus 9p24, 1
Discovery year 1992-04-08
GenBank acession D90239
Entrez gene record 2731
Pubmed identfication 1993704 1996985
RefSeq identity NM_000170
Havana BLAST/BLAT OTTHUMG00000019524
Locus Specific Databases LRG_643

Subscribe to our Newsletter