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GLUR2 Antibody

GLUR2 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenGLUR2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the Ionotropic GLUR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis GLUR2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P42262
PurityAntigen affinity
Description And interruption of the interaction between C-terminal GLUR2 and PDZ domain-containing proteins, As previously demonstrated in rats, GLUR2 plays a major role in depression at synapses in which glutamate remains in the synaptic cleft for prolonged periods of time during normal operation of the synapse, The crystal structures of the GLUR2 ligand-binding core in the apo state and in the presence of the antagonist DNQX, and the full agonists AMPA and glutamate, posttranscriptional change of the sequence at the mRNA level, resulted in increased AMPA receptor-mediated excitatory transmission and blockade of long-term depression, such as GRIP and PICK1, the GLUR2 in human has RNA editing, the partial agonist kainate, Glutamate Receptor 2 is a ligand-activated cation channel protein that mediate the fast component of excitatory postsynaptic currents in neurons of the central nervous system
Immunogen mouse and rat), An amino acid sequence from the middle region of human Glutamate receptor 2 (FQIVDYDDSLVSKFIERW) was used as the immunogen for this GLUR2 antibody (100% homologous in human
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the GLUR2 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetGLUR2
Short nameGLUR2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGLUR2 (Antibody to)
Alternative techniqueantibodies
Identity 4572
Gene GRIA2
Long gene name glutamate ionotropic receptor AMPA type subunit 2
Synonyms gene GLUR2
Synonyms gene name AMPA 2 , glutamate receptor, ionotropic
Synonyms GluA2 GLURB
Locus 4q32, 1
Discovery year 1992-02-26
Entrez gene record 2891
Pubmed identfication 1311100
Classification Glutamate ionotropic receptor AMPA type subunits
Havana BLAST/BLAT OTTHUMG00000133836

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