Name : GPR161 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4093306991
| Long name | GPR161 Primary Polyclonal Antibody |
| Also known as | GPR161 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GPR161 |
| Specificity | This is a highly specific antibody against GPR161 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 165-190/529 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPR161 |
| Gene ID number | 23432 |
| Swiss Prot | Q8N6U8 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | In presence of SHH, Its ligand is unknown (By similarity), Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, it is removed from primary cilia and is internalized into recycling endosomes, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling, preventing its activity and allowing activation of the Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development, Key negative regulator of Shh signaling |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | G-protein coupled receptor 161, G-protein coupled receptor RE2, GPR161, RE2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GPR161 |
| Short name | GPR161 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GPR161 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 23694 |
| Gene | GPR161 |
| Long gene name | G protein-coupled receptor 161 |
| Synonyms | RE2 |
| Locus | 1q24, 2 |
| Discovery year | 2003-12-01 |
| GenBank acession | AF091890 |
| Entrez gene record | 23432 |
| Pubmed identfication | 11959142 |
| RefSeq identity | NM_007369 |
| Classification | Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT | OTTHUMG00000034651 |