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GPS1(Ser474) Antibody

GPS1(Ser474) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGPS1(Ser474) Primary Polyclonal Antibody
Also known asGPS1(Ser474) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGPS1 Ser474
SpecificityThis is a highly specific antibody against GPS1 Ser474
Modification(s)Phosphorylation
Modification site(s)Ser474
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human GPS1 around the phosphorylation site of Ser474
Gene ID number2873
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CSA or DDB2, CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, ITPK1 and IRF8/ICSBP, IkappaBalpha/NFKBIA, Suppresses G-protein-and mitogen-activated protein kinase-mediated signal transduction, The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, The complex is also involved in phosphorylation of p53/TP53, a complex involved in various cellular and developmental processes, c-jun/JUN, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, possibly via its association with CK2 and PKD kinases, respectively, Essential component of the COP9 signalosome complex (CSN)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Arabidopsis Fus6/Cop 11 homolog, Arabidopsis Fus6/Cop 11 homolog, COP9, COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 1, COPS1, COPS1, CSN 1, CSN1_HUMAN, G protein pathway suppressor 1, G protein pathway suppressor 1, GPS-1, GPS1, GPS1, GPS1S474, JAB1-containing signalosome subunit 1, MFH protein, MFH protein, Protein GPS1, Protein MFH, SGN1, Signalosome subunit 1, Y59A8A, constitutive photomorphogenic homolog subunit 1, constitutive photomorphogenic homolog subunit 1, 1, CSN1 phospho S474, p-GPS1Ser474
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGPS1(Ser474)
Short nameGPS1(Ser474) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGPS1(Ser474) (Antibody to)
Alternative techniqueantibodies
Identity 4549
Gene GPS1
Long gene name G protein pathway suppressor 1
Synonyms COPS1 CSN1
Synonyms name COP9 signalosome subunit 1
Locus 17q25, 3
Discovery year 1997-10-10
Entrez gene record 2873
Pubmed identfication 9535219
RefSeq identity NM_212492
Classification COP9 signalosome
Havana BLAST/BLAT OTTHUMG00000178484

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